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New Phosphorylaton Reactions and Protecting Groups for Nucleotides

✍ Scribed by Prof. Dr. F. Cramer; Dipl.-Chem. H. Neunhoeffer; Dipl.-Chem. K. H. Scheit; cand. ing. G. Schneider; cand. ing. J. Tennigkeit


Publisher
John Wiley and Sons
Year
1962
Tongue
English
Weight
118 KB
Volume
1
Category
Article
ISSN
0044-8249

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Nucleotides, Part LXVII , The 2-Cyanoeth
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The amino functions of the common 2'-deoxyribo-and ribonucleosides were blocked by the (2cyanoethoxy)carbonyl group on treatment with 2-cyanoethyl carbonochloridate (5) or 1-[(2-cyanoethoxy)carbonyl]-3-methyl-1H-imidazolium chloride (6) leading to 7, 18, 8, 19, 9, and 20. In 2'-deoxyguanosine, the a