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1-(1-Adamantyl)-1-methylethoxycarbonyl: A New Protecting Group for Peptide Syntheses

✍ Scribed by Dipl.-Chem. Hubert Kalbacher; Prof. Dr. Wolfgang Voelter


Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
235 KB
Volume
17
Category
Article
ISSN
0044-8249

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A new reagent for incorporating the 2-(1
✍ James R. McClure; Maryann K. Sieber πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 135 KB

## A new reagent to incorporate the 2-(1adamantyl)-2-propyloxycarbonyl (Ad-POC) protecting group into amines, 2-(1-adamantyl)-2-propyl p-nitrophenylcarbonate, was prepared in two steps from the commercially available 1-adamantylcarbonyl chloride. The Ad-POC group was introduced into a variety of am