New Oxidative Pathways for the Synthesis of α-Hydroxy Ketones — The α-Hydroxylation and Ketohydroxylation
✍ Scribed by Bernd Plietker
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 9 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The oxidation of α‐hydroxy acids and α‐hydroxy ketones by Br(V) follows the rate‐law However, the former reaction exhibits a second‐order dependence on hydrogen ion concentration while the latter reaction has a third‐order dependence. A mechanism involving a slow formation of a bromate
The enantioselective synthesis of a-aminoand a-hydroxy phosphonates by catalytic processes has attracted considerable interest in the last few years, not least because of the pharmaceutical interest in such compounds. This article contains a compilation of the asymmetric synthesis methods developed