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New one-pot procedure for the synthesis of diprotected amino alcohols from unprotected vinyl aziridines

✍ Scribed by Righi, Giuliana; Bovicelli, Paolo; Tirotta, Ilaria


Book ID
123144301
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
867 KB
Volume
54
Category
Article
ISSN
0040-4039

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## Abstract γ‐Amino alcohols **3** have been synthesized by the addition of organolithium reagents to β‐enamino ketones **1** followed by one‐pot reduction with sodium triacetoxyborohydride. The method allows the stereoselective synthesis of γ‐amino alcohols in which the hydroxy group is bonded to