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One-Pot Addition/Reduction Procedure for the Synthesis of γ-Amino Alcohols from β-Enamino Ketones.

✍ Scribed by Cristina Cimarelli; Sandra Giuli; Gianni Palmieri

Publisher: John Wiley and Sons
Year: 2006
Weight: 22 KB
Volume: 37
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200624081

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## Abstract γ‐Amino alcohols **3** have been synthesized by the addition of organolithium reagents to β‐enamino ketones **1** followed by one‐pot reduction with sodium triacetoxyborohydride. The method allows the stereoselective synthesis of γ‐amino alcohols in which the hydroxy group is bonded to

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## Abstract For Abstract see ChemInform Abstract in Full Text.

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