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New Methods of Resolution and Purification of Racemic and Diastereomeric Amino Alcohol Derivatives Using Boric Acid and Chiral 1,1‘-Bi-2-naphthol

✍ Scribed by Periasamy, Mariappan; Kumar, Nangunoori Sampath; Sivakumar, Sangarappan; Rao, Vutukuri Dharma; Ramanathan, C. Ramaraj; Venkatraman, Lakshmanan


Book ID
120004751
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
82 KB
Volume
66
Category
Article
ISSN
0022-3263

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Chiral 2,2-disubstituted cyclopropanecar
✍ Hyun Chang Kim; Soojin Choi; Hongdoo Kim; Kwang-Hyun Ahn; Jeong Hwan Koh; Jaiwoo 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 190 KB

The enantiomeric purities of secondary alcohols can be easily analyzed by GC and HPLC through derivatization to the esters of 2,2-disubstituted cyclopropanecarboxylic acids 1, and by ~H NMR analysis of the esters of 2,2-diphenylcyclopropanecarboxylic acid (Ib). In addition racemic l,l'-bi-2-naphthol