𝔖 Bobbio Scriptorium
✦   LIBER   ✦

New convenient syntheses of substituted cyclobutenes

✍ Scribed by Leo A. Paquette; J.Christopher Philips


Book ID
104240839
Publisher
Elsevier Science
Year
1967
Tongue
French
Weight
175 KB
Volume
8
Category
Article
ISSN
0040-4039

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✦ Synopsis


In the course of other studies, we required a quantity of &, a hydrocarbon which possesses the unusual structural feature of a cyclobutene ring fused to the 9,10-bond of a hexahydronaphthalene unit. In this cosvnunication, we wish to describe two syntheses of 1 by methods which can be expected to have further utility in the preparation of cyclobutenes frnn acyclic precursors.


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Convenient syntheses of homopropargylgly
✍ Shouliang Dong; Lars Merkel; Luis Moroder; Nediljko Budisa πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 86 KB

## Abstract An improved classic Strecker synthesis was elaborated leading to racemic homopropargylglycine (Hpg) in 61% overall yield, while an asymmetric Strecker reaction produced Hpg and the higher homolog 2‐aminohept‐6‐ynoic acid in significantly higher yields and over 80% ee. Copyright Β© 2008 E