New convenient syntheses of substituted cyclobutenes
β Scribed by Leo A. Paquette; J.Christopher Philips
- Book ID
- 104240839
- Publisher
- Elsevier Science
- Year
- 1967
- Tongue
- French
- Weight
- 175 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
In the course of other studies, we required a quantity of &, a hydrocarbon which possesses the unusual structural feature of a cyclobutene ring fused to the 9,10-bond of a hexahydronaphthalene unit. In this cosvnunication, we wish to describe two syntheses of 1 by methods which can be expected to have further utility in the preparation of cyclobutenes frnn acyclic precursors.
π SIMILAR VOLUMES
## Abstract An improved classic Strecker synthesis was elaborated leading to racemic homopropargylglycine (Hpg) in 61% overall yield, while an asymmetric Strecker reaction produced Hpg and the higher homolog 2βaminoheptβ6βynoic acid in significantly higher yields and over 80% ee. Copyright Β© 2008 E