New convenient reagent for peptide syntheses
β Scribed by Belleau, Bernard.; Malek, G.
- Book ID
- 118066695
- Publisher
- American Chemical Society
- Year
- 1968
- Tongue
- English
- Weight
- 220 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
## Abstract Ten different coupling reagents and their combinations were tested in parallel in the synthesis of four model peptide sequences. Significant differences were found between uronium and phosphonium saltβbased reagents and carbodiimide. Diisopropylcarbodiimide was identified as an optimal
In the course of other studies, we required a quantity of &, a hydrocarbon which possesses the unusual structural feature of a cyclobutene ring fused to the 9,10-bond of a hexahydronaphthalene unit. In this cosvnunication, we wish to describe two syntheses of 1 by methods which can be expected to ha