New convenient, enantiospecific synthesis of (S,S)- and (R,R)-2,2′-bipyrrolidine derivatives
✍ Scribed by Hiyoshizo Kotsuki; Hiroko Kuzume; Tetsushi Gohda; Misako Fukuhara; Masamitsu Ochi; Tohru Oishi; Masahiro Hirama; Motoo Shiro
- Book ID
- 103977262
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 601 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0957-4166
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## Abstract A convenient preparation of (1__R__,2__S__,3__R__,4__S__)‐3‐(neopentyloxy)isoborneol (= (1__R__,2__S__,3__R__,4__S__)‐3‐(2,2‐dimethyl‐propoxy)‐1,7,7‐trimethylbicyclo[2.2.1]heptan‐2‐ol; 1a), a valuable chiral auxiliary, is described. The synthesis involves six steps starting from the rea