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New Chiral α-Benzyloxyacryliron(II) Complex for Asymmetric Synthesis of α, α-Dialkyl-α-hydroxycarbonyl Compounds

✍ Scribed by Felix Stolz; Dr. Peter Strazewski; Prof. Dr. Christoph Tamm; Markus Neuburger; Priv.-Doz. Dr. Margareta Zehnder


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
370 KB
Volume
31
Category
Article
ISSN
0044-8249

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## Abstract Using the __C__~2~‐symmetric bis‐oxazoline copper(II) catalyst **6f** as a chiral Lewis acid, α′‐phosphoric enones **2** undergo 1,3‐dipolar cycloaddition with nitrones **3** to provide isoxazolidines **4** with very high enantioselectivity and __endo/exo__ selectivity.