✦ LIBER ✦
Catalytic Asymmetric 1, 3-Dipolar Cycloaddition Reaction of Nitrones with α′-Phosphoric Enones by a Chiral Ligand- Copper(II) Triflate Complex
✍ Scribed by Kyoung-Chan Lim; Young-Taek Hong; Sunggak Kim
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 212 KB
- Volume
- 350
- Category
- Article
- ISSN
- 1615-4150
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✦ Synopsis
Abstract
Using the C~2~‐symmetric bis‐oxazoline copper(II) catalyst 6f as a chiral Lewis acid, α′‐phosphoric enones 2 undergo 1,3‐dipolar cycloaddition with nitrones 3 to provide isoxazolidines 4 with very high enantioselectivity and endo/exo selectivity.