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New chiral synthon of electrophilic glycine and its reactions with metalloorganic, C-H, N-H, and O-H compounds for the asymmetric synthesis of α-substituted α-amino acids

✍ Scribed by Yu. N. Belokon; A. N. Popkov; N. I. Chernoglazova; V. I. Bakhmutov; M. B. Saporovskaya; V. M. Belikov


Book ID
112446750
Publisher
Springer
Year
1989
Tongue
English
Weight
408 KB
Volume
38
Category
Article
ISSN
1573-9171

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✍ M. Concepción Lozada; Carlos E. Lobato; Raúl G. Enríquez; Benjamín Ortíz; Rubén 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 145 KB

## Abstract The reaction of 2,4‐pentanedione (**1**) with (__R__)‐(—)‐2‐phenylglycine methyl ester (**2**), (__R__)‐(—)‐2‐phenylglycinol (**3**) and the proteinogenic amino acids (2__S__,3__R__)‐(—)‐2‐amino‐3‐hydroxybutyric acid (L‐threonine) (**4**) and (__R__)‐(—)‐2‐amino‐3‐mercaptopropionic acid