Asymmetric Synthesis Employing a Chiral
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Oliver Achatz; Andrea Grandl; Klaus Theodor Wanner
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Article
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1999
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John Wiley and Sons
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English
⚖ 423 KB
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A new asymmetric synthesis of disubstituted α-amino acids From the major diastereomers 17c-d the corresponding αamino acids 19c-d are obtained enantiomerically pure upon is presented. This synthesis is based on the chiral 5-methoxy-1,4-oxazin-2-one derivative 5 relying on the α-hydroxy acid hydroly