ChemInform Abstract: Synthesis of Enantiomerically Pure α-Amino Acids via Chemo- and Diastereoselective Alkylation of (5S)-5-Phenyl-5,6-dihydro-2H-1,4-oxazin-2-one.
✍ Scribed by L. M. HARWOOD; S. N. G. TYLER; A. S. ANSLOW; I. D. MACGILP; M. G. B. DREW
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
A new asymmetric synthesis of disubstituted α-amino acids From the major diastereomers 17c-d the corresponding αamino acids 19c-d are obtained enantiomerically pure upon is presented. This synthesis is based on the chiral 5-methoxy-1,4-oxazin-2-one derivative 5 relying on the α-hydroxy acid hydroly
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