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New Austrian mutation in BRCA1 gene detected in three unrelated HBOC families

✍ Scribed by T.M.U. Wagner; R. Möslinger; C. Zielinski; O. Scheiner; H. Breiteneder

Book ID
118561253
Publisher
The Lancet
Year
1996
Tongue
English
Weight
175 KB
Volume
347
Category
Article
ISSN
0140-6736

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✍ T.M.U. Wagner; R. Möslinger; O. Scheiner; H. Breiteneder; P. Devilee 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 106 KB

Germline mutations in the BRCAl gene confer susceptibility to hereditary breast and ovarian cancer . We report a new mutation in the BRCAl gene in an Austrian hereditary breast and ovarian cancer (HBOC) family with four breast cancer cases and one ovarian cancer in three generations. The average age