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New approach to the synthesis of modified oligonucleotides bearing an aldehyde group

✍ Scribed by Zatsepin, T. S.; Hien, Le Thi; Oretskaya, T. S.


Book ID
110160069
Publisher
Springer
Year
2008
Tongue
English
Weight
124 KB
Volume
419
Category
Article
ISSN
0012-5008

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Different thymidine derivatives bearing either an iodoaryl moiety at the 5 0 position or a dialkylsilyl group at the 3 0 position have been efficiently synthesized as precursors for carbon-11 or fluorine-18 labeling, respectively. Furthermore, iodoarylated thymidine derivatives have been incorporate