New access to thiazolo[4,5-d]pyrimidine
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M. Bakavoli; M. Nikpour; M. Rahimizadeh
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Article
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2006
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Journal of Heterocyclic Chemistry
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English
β 181 KB
## Cl 1 -R 2 NH, EtOH, heat 2 -NaNH 2 , DMF, R'NCS R' 4-Amino-5-bromo-2-substituted-aminopyrimidines are readily obtained from the newly prepared 5bromo-2,4-dichloro-6-methylpyrimidine by sequential treatment with ethanolic ammonia and secondary amines. These compounds were successfully reacted w