Neurotoxicity of combination chemotherapy with procarbazine, CCNU and vincristine (PCV) for recurrent glioma
β Scribed by T.J. Postma; C.J. van Groeningen; R.J.G.M. Witjes; J.G.E. Weerts; J.H. Kralendonk; J.J. Heimans
- Book ID
- 110230361
- Publisher
- Springer US
- Year
- 1998
- Tongue
- English
- Weight
- 294 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0167-594X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Background. The regimen of procarbazine, CCNU, and vincristine is active against gliomas. Previous attempts at dose-intensification have been unsuccesful because of delayed and cumulative myelosuppression. We sought to determine whether peripheral blood stem cell (PBSC) infusions would allow dose-es
## Abstract ## BACKGROUND The efficacy of secondβline chemotherapy for patients with recurrent or progressive oligodendroglial tumors is limited. In the current study, the authors investigated the use of carboplatin as a secondβline chemotherapeutic agent against these types of tumors. ## METHODS