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Chemotherapy of nonirradiated malignant gliomas. Phase II: Study of the combination of methyl-CCNU, vincristine, and procarbazine

โœ Scribed by Anthony M. Avellanosa; Charles R. West; Yoshiaki Tsukada; Donald J. Higby; Surag Bakshi; Peter A. Reese; E. Jennings


Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
1019 KB
Volume
44
Category
Article
ISSN
0008-543X

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Thirty-two patients with advanced, inoperable nonhematologic soft-tissue and osseous sarcomas were treated with Methyl CCNU administered via controlled intravenous infusion in doses of 130-170 mg/m2 every 6 weeks in a Phase I1 trial. All 28 evaluable patients were no longer responsive to adriamycin.