Chemotherapy of nonirradiated malignant gliomas. Phase II: Study of the combination of methyl-CCNU, vincristine, and procarbazine
โ Scribed by Anthony M. Avellanosa; Charles R. West; Yoshiaki Tsukada; Donald J. Higby; Surag Bakshi; Peter A. Reese; E. Jennings
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 1019 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract ## BACKGROUND To the authors' knowledge, there is a scarcity of accurate data regarding the feasibility of standard chemotherapy with procarbazine, lomustine, and vincristine (PCV) in a homogeneous series of patients with primary anaplastic oligodendroglioma (AO) and oligoastrocytoma (
Thirty-two patients with advanced, inoperable nonhematologic soft-tissue and osseous sarcomas were treated with Methyl CCNU administered via controlled intravenous infusion in doses of 130-170 mg/m2 every 6 weeks in a Phase I1 trial. All 28 evaluable patients were no longer responsive to adriamycin.