Dose-intensification of procarbazine, CC
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Jakacki, Regina I.; Jamison, Cheryl; Mathews, Vincent P.; Heilman, Douglas K.; D
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Article
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1998
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John Wiley and Sons
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English
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Background. The regimen of procarbazine, CCNU, and vincristine is active against gliomas. Previous attempts at dose-intensification have been unsuccesful because of delayed and cumulative myelosuppression. We sought to determine whether peripheral blood stem cell (PBSC) infusions would allow dose-es