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Neurotensin mediates mitogenic signaling in human pancreatic cancers

โœ Scribed by Sushovan Guha; Enrique Rozengurt


Book ID
119391123
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
24 KB
Volume
96
Category
Article
ISSN
0002-9270

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โœ Nova M. Ryder; Sushovan Guha; Oscar J. Hines; Howard A. Reber; Enrique Rozengurt ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 363 KB ๐Ÿ‘ 3 views

Neuropeptides and their corresponding G proteinยฑcoupled receptors (GPCRs) are increasingly implicated in the autocrine/paracrine stimulation of growth of human cancers. We report that neurotensin induced rapid Ca 2 mobilization from intracellular stores followed by Ca 2 inยฏux in ยฎve human ductal pan