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Neuroprotective Strategies in Parkinson's Disease Using the Models of 6-Hydroxydopamine and MPTP

✍ Scribed by EDNA GRÜNBLATT; SILVIA MANDEL; MOUSSA B.H. YOUDIM

Book ID
111396233
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
78 KB
Volume
899
Category
Article
ISSN
0890-6564

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This is the first study to investigate the potential protective effects of the lipophilic kavapyrone (+/-)-kavain in the experimental MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) model of Parkinson's disease (PD). Male C57BL/6 mice were treated with (+/-)-kavain (50, 100, or 200 mg/kg i.p.) o