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Neuroprotective effects of novel phosphatidylglycerol-based phospholipids in the 6-hydroxydopamine model of Parkinson's disease

โœ Scribed by S. Crotty; P. Fitzgerald; E. Tuohy; D. M. Harris; A. Fisher; A. Mandel; A. E. Bolton; A. M. Sullivan; Y. Nolan


Book ID
109027281
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
647 KB
Volume
27
Category
Article
ISSN
0953-816X

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โœ Nicole Schmidt; Boris Ferger ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 319 KB ๐Ÿ‘ 2 views

This is the first study to investigate the potential protective effects of the lipophilic kavapyrone (+/-)-kavain in the experimental MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) model of Parkinson's disease (PD). Male C57BL/6 mice were treated with (+/-)-kavain (50, 100, or 200 mg/kg i.p.) o