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Neuroprotective or neurotoxic phenotypes of activated microglia in neonatal mice in neuronal injuries

✍ Scribed by Hirohide Sawada; Hiromi Suzuki; Toshiharu Nagatsu; Makoto Sawada

Book ID
116776948
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
88 KB
Volume
65
Category
Article
ISSN
0168-0102

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## Abstract Estrogen provides neuroprotection against neurodegenerative diseases, including Parkinson's disease. Its effects may stem from interactions with neurons, astrocytes, and microglia. We demonstrate here in primary cultures of rat mesencephalic neurons that estrogen protects them from inju