1031 Estrogen provides neuroprotection against activated microglia-induced dopaminergic neuronal injury through both ERα and ERβ in microglia

Estrogen provides neuroprotection agains

Estrogen provides neuroprotection against activated microglia-induced dopaminergic neuronal injury through both estrogen receptor-α and estrogen receptor-β in microglia

✍ Xuan Liu; Xiao-Lan Fan; Yan Zhao; Guang-Rui Luo; Xu-Ping Li; Rui Li; Wei-Dong Le 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 718 KB

## Abstract Estrogen provides neuroprotection against neurodegenerative diseases, including Parkinson's disease. Its effects may stem from interactions with neurons, astrocytes, and microglia. We demonstrate here in primary cultures of rat mesencephalic neurons that estrogen protects them from inju