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Neuroprotective and anticonvulsant effects of organic and conventional purple grape juices on seizures in Wistar rats induced by pentylenetetrazole

✍ Scribed by Adriana Dalpicolli Rodrigues; Thamiris Becker Scheffel; Gustavo Scola; Maitê Telles dos Santos; Bruna Fank; Suzana Cesa Vieira de Freitas; Caroline Dani; Regina Vanderlinde; João Antonio Pegas Henriques; Adriana Simon Coitinho; Mirian Salvador


Book ID
116765806
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
483 KB
Volume
60
Category
Article
ISSN
0197-0186

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## Abstract Kainic acid (KA)‐induced status epilepticus (SE) is a well‐characterized model of excitotoxic neuronal injury. Excitotoxicity results from activation of specific glutamate receptors, with resultant elevation of intracellular Ca^2+^. The CA1 and CA3 subregions of the hippocampus are espe