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Neuronally-expressed necdin gene: an imprinted candidate gene in Prader-Willi syndrome

✍ Scribed by James S Sutcliffe; Michael Han; Susan L Christian; David H Ledbetter


Book ID
118551137
Publisher
The Lancet
Year
1997
Tongue
English
Weight
262 KB
Volume
350
Category
Article
ISSN
0140-6736

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## Abstract Prader–Willi syndrome (PWS) is caused by loss of paternally expressed genes in the 15q11‐q13 region. To further characterize alterations in gene expression in this classical obesity syndrome we used whole genome microarrays to study a PWS mouse model resulting from a paternally derived