Neuromuscular Junctions in Drosophila

✍ Scribed by Ronald J. Bradley, R. Adron Harris and Peter Jenner (Eds.)

• Publisher: Elsevier, Academic Press
• Year: 1999
• Tongue: English
• Leaves: 317
• Series: International Review of Neurobiology 43
• Category: Library

✦ Synopsis

Neuromuscular Junctions in Drosophila gathers the main contributions that research using the fruit fly Drosophila melanogaster has made in the area of synapse development, synapse physiology, and excitability of muscles and nerve cells. The chapters in this book represent a synthesis of major advances in our understanding of neuronal development and synaptic physiology, which have been obtained using the above approach.This book is directed to the general neuroscience audience: researchers, instructors, graduate students, and advanced undergraduates who are interested in the mechanisms of synapse development and physiology. However, the book will also be a valuable resource for those that use the fruit fly as a model system in their laboratories. Key Features Synthesizes the genetic approaches used to study synaptic development and function at the neuromuscular junction, using flies as a model system Covers major recent advances in muscle development, pathfinding, synapse maturation and plasticity, exo- and endocytosis, and ion channel function Written in clear language that is easily understandable to readers not already familiar with fruit fly research Includes numerous diagrams and extensive reference lists

✦ Table of Contents

Content:
Series Editors
Page ii

Edited by
Page iii

Copyright page
Page iv

Dedication
Page v

Contributors
Pages xi-xii

Preface
Pages xiii-xv
Vivian Budnik, L. Sian Gramates

Early Development of the Drosophila Neuromuscular Junction: A Model for Studying Neuronal Networks in Development Original Research Article
Pages 1-24
Akira Chiba

Development of Larval Body Wall Muscles Original Research Article
Pages 25-44
Michael Bate, Matthias Landgraf, Mar Ruiz Gómez Bate

Development of Electrical Properties and Synaptic Transmission at the Embryonic Neuromuscular Junction Original Research Article
Pages 45-67
Kendal S. Broadie

Ultrastructural Correlates of Neuromuscular Junction Development Original Research Article
Pages 69-92
Mary B. Rheuben, Motojiro Yoshihara, Yoshiaki Kidokorot

Assembly and Maturation of the Drosophila Larval Neuromuscular Junction Original Research Article
Pages 93-100,100a,101-117
L. Sian Gramates, Vivian Budnik

Second Messenger Systems Underlying Plasticity at the Neuromuscular Junction Original Research Article
Pages 119-138
Frances Hannan, Yi Zhong

Mechanisms of Neurotransmitter Release Original Research Article
Pages 139-140,140a,140b,142-161
J. Troy Littleton, Leo Pallanck, Barry Ganetzky

Vesicle Recycling at the Drosophila Neuromuscular Junction Original Research Article
Pages 163-172,172a,173-189
Daniel T. Stimson, Mani Ramaswami

Ionic Currents in Larval Muscles of Drosophila Original Research Article
Pages 191-220
Satpal Singh, Chun-Fang Wu

Development of the Adult Neuromuscular System Original Research Article
Pages 221-226,226a,227-239
Joyce J. Fernandes, Haig Keshishian

Controlling the Motor Neuron Original Research Article
Pages 241-264
James R. Trimarchi, Ping Jin, Rodney K. Murphey

Appendix Larval Body Wall Muscles
Page 265

Index
Pages 267-283