Neuromuscular Junction Disorders
β Scribed by Andrew G. Engel (Eds.)
- Publisher
- Elsevier
- Year
- 2008
- Tongue
- English
- Leaves
- 449
- Series
- Handbook of Clinical Neurology 91
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Synopsis
This volume provides concise and comprehensive information on neuromuscular disorders, including rapid advancements in the understanding of the neurobiology of neuromuscular transmission. In addition, clinicians will find timely discussions on the various forms of these disorders that have been discovered due to increased study within the field.
New observations into the immunopathogenesis of myasthenia gravis, and the molecular mechanisms underlying the links between activity and patterns of gene expression, particularly in muscle, are also explored, along with novel information on the understanding of the pathophysiology of the heterogeneous group of peripheral nerve hyperexcitability syndromes.
Each of these valuable insights, and their accompanying explanations, provides a framework on which new therapeutic strategies can be built to aid in the enhancement and restoration of normal function in neuromuscular junction disorders.
<br><br>* New insights into the study of neuromuscular junction disorders, including rapid advancements in the field<br>* Comprehensive information on the neuromuscular junction, and a detailed examination of myasthenia gravis and other disorders<br>* A new framework upon which to build therapeutic strategies that will enhance the restoration of normal function in neuromuscular disorders
β¦ Table of Contents
Content:
Foreword
Page vii
Michael J. Aminoff, FranΓ§ois Boller, Dick F. Swaab
Preface
Pages ix-x
Andrew G. Engel
Contributors to Volume 91
Page xi
Chapter 1 The most vulnerable synapse: historic aspects of neuromuscular junction disorders Review Article
Pages 1-25
John Keesey
Chapter 2 Reliability of neuromuscular transmission and how it is maintained Review Article
Pages 27-101
Clarke R. Slater
Chapter 3 The neuromuscular junction Review Article
Pages 103-148
Andrew G. Engel
Chapter 4 Electromyographic aspects of neuromuscular junction disorders Review Article
Pages 149-168
C. Michel Harper
Chapter 5 The immunopathogenesis of myasthenia gravis Review Article
Pages 169-212
Norbert Sommer, BjΓΆrn Tackenberg, Reinhard Hohlfeld
Autoantibodies in different forms of myasthenia gravis and in the LambertβEaton syndrome Review Article
Pages 213-227
Angela Vincent
Chapter 7 Clinical features of myasthenia gravis Review Article
Pages 229-252
Donald B. Sanders, Janice M. Massey
Chapter 8 Therapy of myasthenia gravis Review Article
Pages 253-272
Daniel B. Drachman
Chapter 9 The LambertβEaton myasthenic syndrome Review Article
Pages 273-283
Donald B. Sanders, Vern C. Juel
Congenital myasthenic syndromes Review Article
Pages 285-331
Andrew G. Engel
Chapter 11 Botulism Review Article
Pages 333-368
Eric A. Johnson, Cesare Montecucco
Chapter 12 Neurotoxicology of neuromuscular transmission Review Article
Pages 369-400
James F. Howard Jr., Donald B. Sanders
Chapter 13 Organophosphate and carbamate poisoning Review Article
Pages 401-432
Jan L. De Bleecker
Chapter 14 Peripheral nerve hyperexcitability and the neuromuscular junction Review Article
Pages 433-443
Steven Vernino
Subject Index
Pages 445-451
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