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πŸ“

Neuromuscular Junction Disorders

✍ Scribed by Andrew G. Engel (Eds.)


Publisher
Elsevier
Year
2008
Tongue
English
Leaves
449
Series
Handbook of Clinical Neurology 91
Edition
1
Category
Library

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✦ Synopsis


This volume provides concise and comprehensive information on neuromuscular disorders, including rapid advancements in the understanding of the neurobiology of neuromuscular transmission. In addition, clinicians will find timely discussions on the various forms of these disorders that have been discovered due to increased study within the field.

New observations into the immunopathogenesis of myasthenia gravis, and the molecular mechanisms underlying the links between activity and patterns of gene expression, particularly in muscle, are also explored, along with novel information on the understanding of the pathophysiology of the heterogeneous group of peripheral nerve hyperexcitability syndromes.

Each of these valuable insights, and their accompanying explanations, provides a framework on which new therapeutic strategies can be built to aid in the enhancement and restoration of normal function in neuromuscular junction disorders.

                                   <br><br>* New insights into the study of neuromuscular junction disorders, including rapid advancements in the field<br>* Comprehensive information on the neuromuscular junction, and a detailed examination of myasthenia gravis and other disorders<br>* A new framework upon which to build therapeutic strategies that will enhance the restoration of normal function in neuromuscular disorders

✦ Table of Contents


Content:
Foreword
Page vii
Michael J. Aminoff, FranΓ§ois Boller, Dick F. Swaab

Preface
Pages ix-x
Andrew G. Engel

Contributors to Volume 91
Page xi

Chapter 1 The most vulnerable synapse: historic aspects of neuromuscular junction disorders Review Article
Pages 1-25
John Keesey

Chapter 2 Reliability of neuromuscular transmission and how it is maintained Review Article
Pages 27-101
Clarke R. Slater

Chapter 3 The neuromuscular junction Review Article
Pages 103-148
Andrew G. Engel

Chapter 4 Electromyographic aspects of neuromuscular junction disorders Review Article
Pages 149-168
C. Michel Harper

Chapter 5 The immunopathogenesis of myasthenia gravis Review Article
Pages 169-212
Norbert Sommer, BjΓΆrn Tackenberg, Reinhard Hohlfeld

Autoantibodies in different forms of myasthenia gravis and in the Lambert–Eaton syndrome Review Article
Pages 213-227
Angela Vincent

Chapter 7 Clinical features of myasthenia gravis Review Article
Pages 229-252
Donald B. Sanders, Janice M. Massey

Chapter 8 Therapy of myasthenia gravis Review Article
Pages 253-272
Daniel B. Drachman

Chapter 9 The Lambert–Eaton myasthenic syndrome Review Article
Pages 273-283
Donald B. Sanders, Vern C. Juel

Congenital myasthenic syndromes Review Article
Pages 285-331
Andrew G. Engel

Chapter 11 Botulism Review Article
Pages 333-368
Eric A. Johnson, Cesare Montecucco

Chapter 12 Neurotoxicology of neuromuscular transmission Review Article
Pages 369-400
James F. Howard Jr., Donald B. Sanders

Chapter 13 Organophosphate and carbamate poisoning Review Article
Pages 401-432
Jan L. De Bleecker

Chapter 14 Peripheral nerve hyperexcitability and the neuromuscular junction Review Article
Pages 433-443
Steven Vernino

Subject Index
Pages 445-451


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