Neuromuscular Junction

✍ Scribed by Eleanor Zaimis (auth.), Eleanor Zaimis MD., F.R.C.P., Jennifer Maclagan Ph.D. (eds.)

• Publisher: Springer-Verlag Berlin Heidelberg
• Year: 1976
• Tongue: English
• Leaves: 757
• Series: Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology 42
• Edition: 1
• Category: Library

✦ Synopsis

Has the neuromuscular junction been over-exposed or is it perhaps already a closed book? I asked myself this at a recent International Congress when an American colleague complained that the Journal of Physiology had articles on nothing but the neuromuscular junction, while another colleague asked why I was editing a volume on a subject about which everything was already known. It is worrying to think that these views may be shared by other people. I hope that this volume will convince my two colleagues and other readers that the neuromuscular junction is very much alive and continues to attract the interest of many workers from a variety of fields; strange as it may seem, the synapse between a motor nerve ending and muscle fibre, with its relatively simple architecture, is one of the most inter­ esting sites in the body-I do hope we have done it justice. The various chapters of this volume present a cross section of knowledge as viewed by a group of 13 individuals, actively engaged in research. Multi-author volumes such as this are frequently criticised on the grounds that chapters or sec­ tions overlap. I believe that such criticium is only valid where the overlap is repetitious. Where it results in the reader having available discussions of material from differing stand-points, overlap becomes a valuable feature of this type of publication.

✦ Table of Contents

Front Matter....Pages I-XVII
The Neuromuscular Junction: Areas of Uncertainty....Pages 1-21
The Anatomy and Pathology of the Neuromuscular Junction....Pages 23-97
Neurochemistry of Cholinergic Terminals....Pages 99-228
Transmission of Impulses from Nerve to Muscle....Pages 229-364
Depolarising Neuromuscular Blocking Drugs....Pages 365-419
Competitive Neuromuscular Blocking Drugs....Pages 421-486
Pharmacology of Anticholinesterase Drugs....Pages 487-581
The Clinician Looks at Neuromuscular Blocking Drugs....Pages 583-592
Neuromuscular Blocking Drugs in Man....Pages 593-660
Twenty Years’ Experience with Decamethonium....Pages 661-675
Back Matter....Pages 677-748

✦ Subjects

Medicine/Public Health, general; Pharmacy