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Neurodegeneration: How Does Parkin Prevent Parkinson's Disease?

✍ Scribed by Mark R Cookson

Book ID
114319952
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
104 KB
Volume
13
Category
Article
ISSN
0960-9822

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At present, the cause of Parkinson's disease (PD) in most people remains unknown. In some cases, however, a monogenic basis has been identified. These genes can be inherited in an autosomal dominant (eg, a-synuclein, LRRK2) or autosomal recessive (eg, parkin, DJ-1, PINK1, ATP13A2) fashion. Parkin is