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How does parkin ligate ubiquitin to Parkinson's disease?

✍ Scribed by Kahle, Philipp J.; Haass, Christian

Book ID: 110032540
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 71 KB
Volume: 5
Category: Article
ISSN: 1469-221X
DOI: 10.1038/sj.embor.7400188

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At present, the cause of Parkinson's disease (PD) in most people remains unknown. In some cases, however, a monogenic basis has been identified. These genes can be inherited in an autosomal dominant (eg, a-synuclein, LRRK2) or autosomal recessive (eg, parkin, DJ-1, PINK1, ATP13A2) fashion. Parkin is