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Nerve Growth Factor Stimulates the Hydrolysis of Glycosylphosphatidylinositol in PC-12 Cells: A Mechanism of Protein Kinase C Regulation

โœ Scribed by Betty Liwah Chan, Moses V. Chao and Alan R. Saltiel


Book ID
123636729
Publisher
National Academy of Sciences
Year
1989
Tongue
English
Weight
804 KB
Volume
86
Category
Article
ISSN
0027-8424

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Involvement of protein kinase C in nerve
โœ Geneva Dickens; Miriam Lavarreda; Wen-Hua Zheng; Gordon Guroff ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 75 KB ๐Ÿ‘ 2 views

Both nerve growth factor (NGF) and K-252a stimulate the uptake of calcium into PC12 cells. Stimulation by either is prevented by pretreatment of the cells with the tumor promoter phorbol 12-myristate 13-acetate (PMA), suggesting an involvement of protein kinase C in the stimulation. The effect of PM