Analgesic-induced renal papillary necros
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R. A. Axelsen
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Article
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1976
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John Wiley and Sons
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English
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Homozygous Gunn rats, mutant Wistars genetically lacking glucuronyl transferase, develop renal papillary necrosis after single oral doses of aspirin and of phenacetin. The lesion appears significantly more frequently with aspirin than phenacetin, and at lower doses. The model is a convenient one wit