✦ LIBER ✦

Nephrotoxic Effects of Unleaded Petrol in Female Rats

✍ Scribed by A. Vyskocil; M. Cizkova

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 168 KB
Volume: 16
Category: Article
ISSN: 0260-437X
DOI: 10.1002/(sici)1099-1263(199601)16:1<55::aid-jat312>3.0.co;2-4

No coin nor oath required. For personal study only.

✦ Synopsis

Female Wistar rats were exposed to 4 g m-3 unleaded petrol for 8 h a day, 5 days a week for 60 days. Urinary P,-microglobulin ( Pz-m), lactate dehydrogenase (LDH) and lysozyme were used as markers of tubular dysfunction. Urinary excretion of albumin and the glomerular filtration rate (GFR) were used as indicators of glomerular impairment. There were no statistically significant changes in the GFR or urinary albumin concentrations in the exposed group. Petrol exposure induced an increase of Pt-m, total proteins, lysozyme and LDH excretion, but only Pz-m was increased significantly. Our results show that subchronic exposure to high levels of unleaded petrol induced only a mild proximal tubular dysfunction in female rats.

📜 SIMILAR VOLUMES

Reproductive effects of hexachlorobenzen

Reproductive effects of hexachlorobenzene in female rats

✍ Laura Alvarez; Andrea Randi; Paula Alvarez; Gerardo Piroli; Astrid Chamson–Reig; 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 281 KB 👁 1 views

Hexachlorobenzene (HCB) is a polyhalogenated aromatic hydrocarbon widely distributed in the environment. In animal testing, HCB has been shown to be a reproductive toxin. Previous investigations of the effects of HCB on ovarian function have yielded equivocal results. Thus, the effects of chronic ad

Protective Effects of Methimazole agains

Protective Effects of Methimazole against Cisplatin-induced Nephrotoxicity in Rats

✍ Helmut Bräunlich; Dorothea Appenroth; Christian Fleck 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 159 KB 👁 1 views

Key words: nephrotoxicity; cisplatin; radical scavengers; methimazole; rat In adult rats 6 mg kg -1 body wt. cisplatin given i.p. was nephrotoxic. Four days of i.p. treatment with 40 mg kg -1 body wt. methimazole, which started 1 day before CP, prevented increases in blood urea nitrogen and in the r

Effects of agonistic experience in rats

✍ N. E. De Van Poll; J. G. Van Oyen; H. J. Smeets; F. H. De Jonge 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 164 KB 👁 2 views

Ganglioside lateralization in the brain

Ganglioside lateralization in the brain of female rats

✍ P. Palestini; N. Toppi; A. Ferraretto; M. Pitto; M. Masserini 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 81 KB 👁 1 views

The ganglioside composition of the cerebral hemispheres of young and adult rats of either sex has been herein assessed for the first time. In females, the total ganglioside content at any age, the content of GM1, GD1a, and GD1b at 8 days, and the content of GM1, GD1b, GT1b, and GQ1b at 60 days were

Reversible Antifertility Effects of Benz

Reversible Antifertility Effects of Benzene Extract of Papaya Seed on Female Rats

✍ Harsha Joshi; N. J. Chinoy 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 184 KB 👁 1 views

The effects of benzene extract from papaya seeds and those of withdrawal (30 days each) were investigated on the physiology of ovaries and uterus of rats and their fertility. The results revealed that the treatment did not affect ovarian steroidogenesis. On the other hand, uterine glycogen, protein

Comparative nephrotoxicity of some antit

Comparative nephrotoxicity of some antitumour-active platinum and ruthenium complexes in rats

✍ Lothar Kersten; Helmut Bräunlich; Bernhard K. Keppler; Christiane Gliesing; Matt 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 206 KB 👁 1 views

Key words: nephrotoxicity; platinum(II) complexes; ruthenium(III) complexes; rats. The nephrotoxicity of three platinum (CPL, KP734, KP735) and three ruthenium coordination complexes (KP418, KP692, KP1019) was tested in rats in comparison to cisplatin (CP). Renal functional changes (excretion of wa