✦ LIBER ✦

Reversible Antifertility Effects of Benzene Extract of Papaya Seed on Female Rats

✍ Scribed by Harsha Joshi; N. J. Chinoy

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 184 KB
Volume: 10
Category: Article
ISSN: 0951-418X
DOI: 10.1002/(sici)1099-1573(199606)10:4<327::aid-ptr825>3.0.co;2-b

No coin nor oath required. For personal study only.

✦ Synopsis

The effects of benzene extract from papaya seeds and those of withdrawal (30 days each) were investigated on the physiology of ovaries and uterus of rats and their fertility. The results revealed that the treatment did not affect ovarian steroidogenesis. On the other hand, uterine glycogen, protein and enzymes were altered which rendered the internal milieu hostile for implantation. The extract manifested an antifertility effect in treated animals. The withdrawal of treatment resulted in recovery of all the induced effects of the extract and restored fertility. Hence, the antifertility effects of the extract were transient and reversible. This is the first report of its kind using the benzene extract of the seed.

📜 SIMILAR VOLUMES

Studies on antifertility effect of pawpa

Studies on antifertility effect of pawpaw seeds (Carica papaya) on the gonads of male albino rats

✍ Dr Paul Udoh; Akinrogunde Kehinde 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 206 KB 👁 2 views

Preliminary studies on the antifertility effect of pawpaw seeds (Carica papaya) on the gonads of male albino (Wistar) rats was investigated. An oral dose of crude ripe pawpaw seeds at 100 mg/kg body weight and 50 mg/kg body weight were administered orally for 8 weeks. Histological observations at a

Effect of Water Extract of Cardiospermum

Effect of Water Extract of Cardiospermum grandiflorum Swartz on the Gravid Female Rat Uterus

✍ Guede Noel Zirihi; Mansoor Ahmad 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 234 KB 👁 2 views

The effect of a water extract of Cardiospermum grandijlorum Swartz (Sapindaceae) was investigated on a gravid female ratuherus. This extract showed a strong elevation in contractile activity, inhibited by atropine, of the female (pregnant) Wistar rat uterus. It was found to be dose dependent.

Effects of extracts of seed and leaf of

Effects of extracts of seed and leaf of Piper guineense on skeletal muscle activity in rat and frog

✍ Francis V. Udoh; Theodore Y. Lot; Victor B. Braide 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 272 KB 👁 2 views

The pharmacological effects of leaf and seed extracts of Piper guineense were investigated on phrenic nerve hemidiaphragm activity following electrical stimulation in vitro. The Leaf and seed extracts (10 mg -1 mg/mL) and (50 -800 mg/mL) respectively produced biphasic effects consisting of an initi

Endothelium-dependent vasodilator effect

Endothelium-dependent vasodilator effect of extract prepared from the seeds of Areca catechu on isolated rat aorta

✍ Hirozo Goto; Nobumitsu Tanaka; Kiyoaki Tanigawa; Yutaka Shimada; Takashi Itoh; K 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 62 KB 👁 1 views

Arecae semen extract relaxed aortic ring preparations of isolated rat aorta that contained endothelium from 3ϫ 10 Ϫ 7 g/mL, reaching a maximum of 86% at 10 Ϫ 5 g/mL. Its relaxation did not occur in specimens without endothelium, and was inhibited by pretreatment with 10 Ϫ 4 M N G -nitro-1-arginine m