Need and potential value of the Pig-ain vivo mutation assay—A hesi perspective
✍ Scribed by Maik Schuler; B. Bhaskar Gollapudi; Véronique Thybaud; James H. Kim
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 110 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0893-6692
- DOI
- 10.1002/em.20687
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract We previously reported that rat spleen T‐cells and peripheral red blood cells that are deficient in glycosylphosphatidylinositol (GPI) synthesis [presumed mutants for the phosphatidylinositol glycan complementation group A gene (__Pig‐A__)] could be detected by flow cytometry (FCM) as c
Three genotoxic mouse carcinogens, 4 c h l o r wphenylenediamine (4-C-o-PDA), 2-nitro-p-phenylenediamine (2-N-pPDA), and 2,4diaminotoluene (2,4-DAT), were tested in the Big BlueTM transgenic mouse mutation assay. Each experiment consisted of a vehicle control group with ten Big BlueTM C57BL/6 mice,