The in vivo pig-a gene mutation assay, a potential tool for regulatory safety assessment
β Scribed by Vasily N. Dobrovolsky; Daishiro Miura; Robert H. Heflich; Stephen D. Dertinger
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 608 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0893-6692
- DOI
- 10.1002/em.20627
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## Abstract We previously reported that rat spleen Tβcells and peripheral red blood cells that are deficient in glycosylphosphatidylinositol (GPI) synthesis [presumed mutants for the phosphatidylinositol glycan complementation group A gene (__PigβA__)] could be detected by flow cytometry (FCM) as c
The X-linked hypoxanthine-guanine phosphoribosyl-respectively. These data were similar to the reported transferase (hprt) gene is a target of analyses of in values. The mean MFs in the nine colon cancer pavivo mutation frequencies in circulating T-lympho-tients (10.6 { 7.3 1 10 06 ) were not signifi