Biochemical studies utilizing keloid fibroblast cultures revealed that Nd:YAG laser selectively suppressed collagen production by these cells. Based on these in vitro observations. eight patients with keloids were treated with Nd:YAG laser in a nondestructive manner. Results, with a 3-year follow-up
Nd:YAG laser in caries prevention: A clinical trial
β Scribed by Denise Maria Zezell; Heloisa Gomes D. Boari; Patricia Aparecida Ana; Carlos de Paula Eduardo; Glen Lynn Powell
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 101 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0196-8092
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Background and Objective
It is widely known that Nd:YAG can increase enamel resistance to demineralization; however, there are no studies that report the application of Nd:YAG associated with topical application of fluoride in vivo. The aim of this study was to evaluate the effects of the Nd:YAG laser, when associated with the topical application of acidulated phosphate fluoride (APF), for preventing enamel demineralization in vivo.
Materials and Methods
A doubleβblind crossover experimental design was used, in which 121 teeth of 33 volunteers were selected. In all volunteers, the right side teeth were selected for Nd:YAG laser+APF application (lased group) and the left side teeth were kept as control group (only APF application). Nd:YAG laser was applied at 60 mJ/pulse, at a repetition rate of 10 Hz and fluence of 84.9 J/cm^2^; after that, topical APF was applied for 4 minutes. Recalls were made after 1 year in order to evaluate the formation of whiteβspot lesions or caries cavities.
Results
After 1 year, this in vivo experiment showed a reduction of 39.2% in caries incidence in lased group when compared with the control. The number of whiteβspots or caries cavities decreased significantly (Pβ=β0.0043) in the Nd:YAG laser group; the formation of whiteβspots was significantly less (Pβ=β0.0031) when compared with the number of lesions in the control group.
Conclusion
Combined Nd:YAG laser and topical fluoride treatment was effective for reducing the incidence of caries in vivo. Lasers Surg. Med. 41:31β35, 2009. Β© 2008 WileyβLiss, Inc.
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