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Laser treatment of keloids: A clinical trial and an in vitro study with Nd:YAG laser

✍ Scribed by R. Patrick Abergel; Richard M. Dwyer; Cheryl A. Meeker; Jouni Uitto; Gary Lask; A. Paul Kelly


Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
362 KB
Volume
4
Category
Article
ISSN
0196-8092

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✦ Synopsis


Biochemical studies utilizing keloid fibroblast cultures revealed that Nd:YAG laser selectively suppressed collagen production by these cells. Based on these in vitro observations. eight patients with keloids were treated with Nd:YAG laser in a nondestructive manner. Results, with a 3-year follow-up, indicated flattening and softening of the lesions. Thus, the results suggest that Nd:YAG laser is an effective treatment modality for keloids, and its mechanism may involve bioinhibition of fibroblast functions.


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