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Nature of the pH-induced conformational changes and exposure of the C-terminal region of chromogranin A

โœ Scribed by Seung Hyun Yoo; James A. Ferretti


Book ID
115927874
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
798 KB
Volume
334
Category
Article
ISSN
0014-5793

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The C-terminal domain of the heterotrimeric G protein a-subunits plays a key role in selective activation of G proteins by their cognate receptors. Several C-terminal fragments of Galpha(s) (from 11 to 21 residues) were recently synthesized. The ability of these peptides to stimulate agonist binding