Nature of Melittin-Phospholipid Interaction
β Scribed by Georghiou, S.; Thompson, M.; Mukhopadhyay, A.K.
- Book ID
- 118518203
- Publisher
- Biophysical Society
- Year
- 1982
- Tongue
- English
- Weight
- 372 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0006-3495
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π SIMILAR VOLUMES
The sonicated dispersion of phospholipids in water is found to form a 1:1 molecular complex with iodine when the concentration of phospholipid is above the critical value (1.6Γ 10-5moldm-3). From thermodynamic as well as spectrophotometric studies, the electron donating property of several phospboli
In aqueous solution, melittin structure, investigated by CD and 'H-nmr, depends on pH and ionic composition, which also regulate the aggregation state of the peptide. When interacting with phospholipids, however, melittin exhibits a right-handed helical conformation without any evidence of oligomeri