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Natural killer cell cytotoxicity is not regulated by folic acid in vitro

✍ Scribed by Hirsch, Sandra; Miranda, Dante; Muñoz, Estefanía; Montoya, Margarita; Ronco, Ana María; de la Maza, María Pía; Bunout, Daniel

Book ID
120039959
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
176 KB
Volume
29
Category
Article
ISSN
0899-9007

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Considerable evidence has accumulated for a role of a nonsteroidal mevalonate product in the regulation of DNA replication and cell division. We report here a similar requirement for mevalonate in a nonreplicative function, that of natural killer (NK) cell cytotoxicity. Treatment of NK cells with 10