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ROLE OF INTERFERON IN REGULATION OF CYTOTOXICITY BY NATURAL KILLER CELLS AND MACROPHAGES

✍ Scribed by Ronald B. Herberman; John R. Ortaldo; Julie Y. Djeu; Howard T. Holden; James Jett; Nicholas P. Lang; Menachem Rubinstein; Sidney Pestka

Book ID
118718197
Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
508 KB
Volume
350
Category
Article
ISSN
0890-6564

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Considerable evidence has accumulated for a role of a nonsteroidal mevalonate product in the regulation of DNA replication and cell division. We report here a similar requirement for mevalonate in a nonreplicative function, that of natural killer (NK) cell cytotoxicity. Treatment of NK cells with 10