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Nanofluidic devices towards single DNA molecule sequence mapping

โœ Scribed by Rodolphe Marie; Anders Kristensen


Book ID
112117869
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
394 KB
Volume
5
Category
Article
ISSN
1864-063X

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## Abstract **One's enough**: The direct observation of a DNAโ€polymeraseโ€based โ€œsequencing engineโ€ using singleโ€molecule detection recently allowed singleโ€molecule sequencing by synthesis in real time. Nucleotides with a fluorescent marker at the 5โ€ฒโ€phosphate unit and zeroโ€mode waveguides are cruci