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Nanofluidic system for the studies of single DNA molecules

✍ Scribed by Chiung-Wen Kuo; Kung Hwa Wei; Chun-Hsun Lin; Jau-Ye Shiu; Peilin Chen


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
547 KB
Volume
29
Category
Article
ISSN
0173-0835

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## Abstract Single molecule microscopy techniques play an important role in the investigation of advanced DNA structures such as those created by the DNA origami method. Three single molecule microscopy techniques are particularly interesting for the investigation of complex self‐assembled three‐di

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## Communicated by Richard Cotton Determining the haplotypes in a diploid individual is a major technical challenge in genetic studies of human complex traits. Here we report a method of molecular haplotyping by directly imaging multiple polymorphic sites on individual DNA molecules simultaneously