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Naltrexone: No effect on simian social and motor behavior

✍ Scribed by Thomas J. Crowley; Marilyn J. Macdonald; Gary Zerbe

Publisher
Springer
Year
1985
Tongue
English
Weight
179 KB
Volume
87
Category
Article
ISSN
0033-3158

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✦ Synopsis

Persisting opioid agonists modify monkeys' social and motor behavior (Crowley et al. 1975; Crowley et al. 1985a), suggesting that opioid systems might partially regulate motility and social intercourse. If so, blockade of the response of opioid receptors to endogenous opioid agonists might alter motor and social behavior in a direction opposite from that produced by agonists. To test that hypothesis, we have treated group-living monkeys with naltrexone, a long-acting opioid antagonist. The drug did not appear to change social or motor behavior.

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