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NAD(P+/NAD(P)H Models. 83. Molecular Asymmetry with a Carbonyl Group: Electronically Controlled Stereochemistry in the Reaction of NAD(P)+/NAD(P)H Analogs

✍ Scribed by Ohno, Atsuyoshi; Tsutsumi, Akihiro; Kawai, Yasushi; Yamazaki, Norimasa; Mikata, Yuji; Okamura, Mutsuo


Book ID
126000299
Publisher
American Chemical Society
Year
1994
Tongue
English
Weight
567 KB
Volume
116
Category
Article
ISSN
0002-7863

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NAD(P)+–NAD(P)H models. 84. Stereochemis
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## 2,3-Dihydro-2,2,4-trimethylthieno[3,2-b]pyridinium I-oxide iodide (1) has been reacted with various inorganic and organic hydride donors. It has been found that the stereochemistry of reaction is controlled by the orientation of the sulfinyl dipole, and the relative bulkiness of substituents pl

A model study of the role of the CONH2-g
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## Abstract A model is offered for the role of the CONH~2~‐group in the stereospecific incorporation of hydride at C(4) in NAD(P)^+^‐like compounds.