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NADH Oxidase Activity of Human Xanthine Oxidoreductase : Generation of Superoxide Anion

✍ Scribed by Stephen A. Sanders; Robert Eisenthal; Roger Harrison

Book ID
115133499
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
911 KB
Volume
245
Category
Article
ISSN
1432-1327

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Bovine brain endothelial cells (EC) that were isolated and propagated in pure culture had increased (> 20-fold) levels of xanthine oxidase and xanthine dehydrogenase activity compared to whole brain homogenate. Brain EC also released superoxide anion (0;) into the extracellular medium. Treatment of