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N-trichloroacetoxyphthalimide as a new reagent for the synthesis of the N-hydroxyphthalimide esters of N-protected amino acids

✍ Scribed by A. V. Il'ina; Yu. A. Davidovich; S. V. Rogozhin


Book ID
112442419
Publisher
Springer
Year
1984
Tongue
English
Weight
277 KB
Volume
33
Category
Article
ISSN
1573-9171

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Synthesis and reactions of esters of N-h
✍ G. H. L. Nefkens; G. I. Tesser; R. J. F. Nivard 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 313 KB

## Abstract Esters can be prepared from __N__‐hydroxyphthalimide and __N__‐carbobenzoxy‐ or __N__‐phthaloyl‐amino acids using dicyclohexylcarbodi‐imide as condensing agent. The compounds are suitable for the stepwise synthesis of peptides without racemization. With methanol the __N__‐hydroxyphthali